Sign In or Create an Account. Sign In. Advanced Search. Search Menu. Article Navigation. Close mobile search navigation Article Navigation. Volume Article Contents Variation in Fracture Rates. Challenges in Studying Ethnicity. Ethnic Differences in BMD. Genetic Factors in BMD. Anthropometry and BMD. Ethnic Differences in Calciotropic and Gonadal Hormones.
Lifestyle and Social Factors. Ethnic Differences in Osteoporosis Care. Advanced Imaging Techniques. Implications for Fracture Risk Assessment. Leslie William D. Leslie, M. Oxford Academic. Cite Cite William D. Select Format Select format. Permissions Icon Permissions.
Open in new tab Download slide. Table 1. Factors that contribute to ethnic differences in BMD and fracture risk. White women Open in new tab. Area under the receiver operating characteristic. Search ADS.
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Advanced Search. Search Menu. Article Navigation. Close mobile search navigation Article Navigation. Volume Article Contents I Introduction.
III Pathogenesis of Fractures. V Genetic Architecture of Osteoporosis. XI Gene-Gene Interactions. Note Added in Proof. Genetics of Osteoporosis. Ralston , Stuart H. Ralston, M. Oxford Academic. Cite Cite Stuart H. Select Format Select format. Permissions Icon Permissions. Open in new tab Download slide. Open in new tab. Caucasian USA. Gene s. Novel a. Spine BMD. Hip BMD. Fracture b. Mode of identification c. Google Scholar Crossref. Search ADS. Identification and fracture outcomes of undiagnosed low bone mineral density in postmenopausal women: results from the National Osteoporosis Risk Assessment.
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Download references. Schlieder Endowment fund to Tulane University. You can also search for this author in PubMed Google Scholar. Yu-Mei Li performed the statistical analyses of the data and wrote the manuscript.
Cheng Peng provided a critical review of the manuscript. Ji-Gang Zhang provided methodological input and a critical review of the manuscript. Wei Zhu collected the data. Chao Xu performed the statistical analyses of the data. Yong Lin performed the statistical analyses of the data. Xiao-Ying Fu collected the data. Qing Tian collected the data. Lei Zhang collected the data. Yang Xiang collected the data. Victor Sheng provided a critical review of the manuscript. Hong-Wen Deng designed the study, provided a critical review of the manuscript.
Reprints and Permissions. Li, YM. Genetic risk factors identified in populations of European descent do not improve the prediction of osteoporotic fracture and bone mineral density in Chinese populations. Sci Rep 9, Download citation. Received : 23 May Accepted : 03 April Published : 15 April Anyone you share the following link with will be able to read this content:. Sorry, a shareable link is not currently available for this article.
Provided by the Springer Nature SharedIt content-sharing initiative. Genome Medicine By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate. Advanced search. Skip to main content Thank you for visiting nature. Download PDF. Subjects Clinical genetics Predictive medicine. Abstract Aiming to investigate whether genetic risk factors GRFs for fracture and bone mineral density BMD identified from people of European descent can help improve the prediction of osteoporotic fracture OF risk and BMD in Chinese populations, we built assessment models for femoral neck FN -fracture prediction and BMD value prediction using elderly Chinese Han subjects and 1, unrelated Chinese Han subjects, respectively.
Introduction Osteoporosis OP is a chronic disease characterized by low bone mineral density BMD and an increased risk of fracture.
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