Rectal use of a drug involves the insertion of the drug into the rectum, where it can dissolve and be absorbed into the bloodstream via the linings of the rectum. In medical use, drugs are sometimes administered this way to patients who cannot swallow. Recreational use of this type of administration is not widespread. Absorption is usually relatively slow.
Comments will be used to improve web content and will not be responded to. Thank you for taking the time to provide feedback. It will be used to make improvements to this website. Table of contents Section A. Examples of such chemicals include mephedrone, methylone, and 3,4-methylenedioxypyrovalerone MDPV. For more information, see the Synthetic Cathinones DrugFacts. Tobacco and Nicotine Tobacco is a plant grown for its leaves, which are dried and fermented before use. Tobacco contains nicotine, an addictive chemical.
Nicotine is sometimes extracted from the plant and is used in vaping devices. National Institutes of Health. Drug Topics. More Drug Topics. Quick Links. About NIDA. Commonly Used Drugs Charts. Expand All. August 20, Strong hallucinations including altered visual and auditory perceptions; increased heart rate and blood pressure; nausea; burning sensation in the stomach; tingling sensations and increased skin sensitivity. Possible changes to the serotoninergic and immune systems, although more research is needed.
It is not known whether ayahuasca is addictive. There are no FDA-approved medications to treat addiction to ayahuasca or other hallucinogens. More research is needed to find out if ayahuasca is addictive and, if so, whether behavioral therapies are effective.
Drowsiness, slurred speech, poor concentration, confusion, dizziness, problems with movement and memory, lowered blood pressure, slowed breathing. Sleep medications are sometimes used as date rape drugs. Must be discussed with a health care provider; barbiturate withdrawal can cause a serious abstinence syndrome that may even include seizures.
There are no FDA-approved medications to treat addiction to prescription sedatives; lowering the dose over time must be done with the help of a health care provider. More research is needed to find out if behavioral therapies can be used to treat addiction to prescription sedatives.
Cocaine hydrochloride topical solution low dose anesthetic used in certain medical procedures. Narrowed blood vessels; enlarged pupils; increased body temperature, heart rate, and blood pressure; headache; abdominal pain and nausea; euphoria; increased energy, alertness; insomnia, restlessness; anxiety; erratic and violent behavior, panic attacks, paranoia, psychosis; heart rhythm problems, heart attack; stroke, seizure, coma. Loss of sense of smell, nosebleeds, nasal damage and trouble swallowing from snorting; infection and death of bowel tissue from decreased blood flow; poor nutrition and weight loss; lung damage from smoking.
Pregnancy: premature delivery, low birth weight , deficits in self-regulation and attention in school-aged children prenatally exposed. Depression, tiredness, increased appetite, insomnia, vivid unpleasant dreams, slowed thinking and movement, restlessness. Intense visual hallucinations, depersonalization, auditory distortions, and an altered perception of time and body image, usually peaking in about 30 minutes when drank as tea.
Physical effects include hypertension, increased heart rate, agitation, seizures, dilated pupils. It is not known whether DMT is addictive. More research is needed to find out if DMT is addictive and, if so, whether behavioral therapies are effective. Euphoria, drowsiness, nausea, vomiting, confusion, memory loss, unconsciousness, slowed heart rate and breathing, lower body temperature, seizures, coma, death. Insomnia, anxiety, tremors, sweating, increased heart rate and blood pressure, psychotic thoughts.
Collapsed veins; abscesses swollen tissue with pus ; infection of the lining and valves in the heart; constipation and stomach cramps; liver or kidney disease; pneumonia. Pregnancy: miscarriage, low birth weight, neonatal abstinence syndrome.
Restlessness, muscle and bone pain, insomnia, diarrhea, vomiting, cold flashes with goose bumps "cold turkey". Methadone Buprenorphine Naltrexone short- and long-acting forms. Various household products Amyl nitrite a prescription solution is used to relieve pain of angina attacks chest pain.
Paint thinners or removers, degreasers, dry-cleaning fluids, gasoline, lighter fluids, correction fluids, permanent markers, electronics cleaners and freeze sprays, glue, spray paint, hair or deodorant sprays, fabric protector sprays, aerosol computer cleaning products, vegetable oil sprays, butane lighters, propane tanks, whipped cream aerosol containers, refrigerant gases, ether, chloroform, halothane, nitrous oxide, prescription nitrites.
Nitrites: enlarged blood vessels, enhanced sexual pleasure, increased heart rate, brief sensation of heat and excitement, dizziness, headache. Liver and kidney damage; bone marrow damage; limb spasms due to nerve damage; brain damage from lack of oxygen that can cause problems with thinking, movement, vision, and hearing.
Nitrites: increased risk of pneumonia. Pregnancy: low birth weight, bone problems, delayed behavioral development due to brain problems, altered metabolism and body composition. More research is needed to find out if behavioral therapies can be used to treat inhalant addiction. When misused: Injected, snorted, smoked powder added to tobacco or marijuana cigarettes , swallowed Prescription formulas are injections or nasal sprays.
Nicotine is the main addictive ingredient of tobacco. When somebody smokes a cigarette, nicotine is rapidly absorbed by the lungs and delivered to the brain.
More than two-thirds of Americans who tried smoking reported becoming dependent during their life. In the WHO estimated there were more than 1 billion smokers and it has been estimated that tobacco will kill more than 8m people annually by Laboratory animals have the good sense not to smoke. Barbiturates — also known as blue bullets, gorillas, nembies, barbs and pink ladies — are a class of drugs that were initially used to treat anxiety and to induce sleep.
They interfere with chemical signalling in the brain, the effect of which is to shut down various brain regions. Prescription opioids and heroin. Updated January PLoS One.
Fentanyls continue to replace heroin in the drug arena: the cases of ocfentanil and carfentanil. Forensic Toxicol. Shewan D, Dalgarno P. Evidence for controlled heroin use? Low levels of negative health and social outcomes among non-treatment heroin users in Glasgow Scotland. Br J Health Psychol. Updated August American Psychiatric Association.
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False Feelings. Pain Relief. Dangerous Effects. Harm Reduction. Heroin Addiction. The Short-Term Effects of Heroin. Was this page helpful? Thanks for your feedback! Sign Up.
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